Table 8.

Multivariate Cox regression analysis of survival rate in SC/ASC and AC patients.

Groups	Factors	SC/ASC		AC
		P	HR (95%CI)	P	HR (95%CI)
Differentiated degree	Well/moderately/poorly	0.008	1.813 (1.166–2.818)	0.001	1.567 (1.193–2.057)
Tumor size	≤3 cm/>3 cm	0.022	2.560 (1.148–5.707)	0.012	1.865 (1.149–3.026)
Gallstone	No/Yes	0.047	1.770 (1.009–3.107)	0.005	1.728 (1.181–2.528)
TNM stage	I + II/III + IV	0.023	2.504 (1.134–5.528)	0.017	2.399 (1.171–4.915)
Lymph node metastasis	No/Yes	0.018	3.155 (1.222–8.147)	0.011	2.394 (1.220–4.698)
Invasion	No/Yes	0.027	3.394 (1.150–10.013)	0.000	5.795 (2.913–11.530)
Surgery	Radical/Palliative/Biopsy	0.006	2.192 (1.254–3.833)	0.000	2.540 (1.679–3.840)
XBP1	–/+	0.012	2.305 (1.205–4.409)	0.003	1.848 (1.227–2.783)
NAT1	–/+	0.015	0.351 (0.151–0.813)	0.000	0.472 (0.312–0.714)

–, negative expression; +, positive expression; HR, hazard ratio; CI, confident interval.