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. 2020 Jul 24;10:1122. doi: 10.3389/fonc.2020.01122

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Copyright © 2020 D'Angelo, Lindoso, Sensi, Pucciarelli, Bussolati, Agostini and Collino.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Example of a therapeutic approach based on the targeting of tumor extracellular vesicles (EVs). Inhibition of the EV uptake by SKOV-3 cells treated with increased concentrations of LXY30 peptide (A) by measuring fluorescence intensity in target cells *p < 0.005. (B–F) Representative laser scanning microscope images of SKOV-3 cells treated with unlabeled (B) or labeled DiL-EV in combination with different concentrations (C–F) of LXY30 peptide. Contribution from Carney et al. (168). Copyright Wiley-VCH Verlag GmbH & Co. KGaA. Reproduced with permission.