Fig. 2.

Brain MRI findings in the three siblings. T2-weighted images obtained during the acute encephalopathy (top row – Sibling 1, middle – Sibling 2, bottom – Sibling 3). Abnormal signals were visible in the brainstem [pons & midbrain] (blue arrow), lateral geniculate nuclei (yellow arrow), temporal lobes (green arrow), thalami (red arrow), external capsules (purple arrow) and insular cortices (orange arrow). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)