Table 3.
Neonatal outcomes according to exposure to antenatal MgSO4 treatment.
| MgSO4 unexposed | MgSO4 exposed | P value | aOR (95% CI)1 | P value | ||
|---|---|---|---|---|---|---|
| NEC (≥ stage 2b) | All infants | 26/509 (5.1) | 9/247 (3.6) | 0.369 | 0.70 (0.31‒1.55) | 0.373 |
| PTB < 26 weeks | 16/122 (13.1) | 2/50 (4.0) | 0.076 | 0.27 (0.06‒1.28) | 0.100 | |
| PTB 26‒31 weeks | 10/387 (2.6) | 7/197 (3.6) | 0.510 | 1.19 (0.43‒3.27) | 0.734 | |
| NEC perforation | All infants | 18/509 (3.5) | 5/247 (2.0) | 0.256 | 0.58 (0.21‒1.64) | 0.306 |
| PTB < 26 weeks | 13/122 (10.7) | 1/50 (2.0) | 0.059 | 0.18 (0.02‒1.47) | 0.109 | |
| PTB 26‒31 weeks | 5/387 (1.3) | 4/197 (2.0) | 0.494 | 1.32 (0.34‒5.08) | 0.691 | |
| SIP | All infants | 9/509 (1.8) | 7/247 (2.8) | 0.340 | 1.82 (0.65‒5.10) | 0.252 |
| PTB < 26 weeks | 4/122 (3.3) | 2/50 (4.0) | 1.000 | 1.13 (0.19‒6.69) | 0.894 | |
| PTB 26‒31 weeks | 5/387 (1.3) | 5/197 (2.5) | 0.317 | 2.35 (0.64‒8.57) | 0.196 | |
Data are presented as number (percentage).
MgSO4 magnesium sulfate, aOR adjusted odds ratio, CI confidence interval, NEC necrotizing enterocolitis, PTB preterm birth, SIP spontaneous intestinal perforation.
1Adjusted for plurality, antenatal corticosteroids treatment, nifedipine treatment, and gestational age at delivery.