Table 2.

Assessment of DCB-PTA Versus PTA on Plaque Progression

	DCB-PTA vs. PTA (Unadjusted)			DCB-PTA vs. PTA (∗Adjusted)
	Estimate	95% Confidence Intervals	p Value	Estimate	95% Confidence Intervals	p Value
Δ Total atheroma volume (mm3)	−1,14.5	−152.4 to −76.6	<0.001†	−114.0	−159.6 to −68.4	<0.001†
Δ Percent atheroma volume (%)	−8.5	−12.7 to −4.4	<0.001†	−8.2	−11.7 to −4.7	<0.001†
Δ Average plaque burden (%)	−7.3	−12.1 to −2.5	0.005‡	−7.0	−11.6 to −2.4	0.006‡

Unadjusted and adjusted estimates comparing the changes in total atheroma value, percent atheroma value and plaque burden in DCB-PTA vs. PTA (measured as Δ change) derived from generalized linear regression models with 95% confidence intervals.

Abbreviations as in Table 1.

^∗Adjusted for baseline cholesterol, C-reactive protein, and minimal lumen area, and corresponding atheroma parameter at baseline (6 weeks).

^†p < 0.001;

^‡p < 0.01.