Table 3.

Assessment of DCB-PTA Versus PTA on NIRF Plaque Inflammation, and Relationships Between Plaque NIRF Inflammation and Plaque Progression

Unadjusted and Adjusted Regression Estimates Comparing the Percentage Change Difference in Δ NIRF inflammation Between DCB-PTA vs. PTA (measured as Δ change)
	% Change (95% CI)	p Value
Δ NIRF (unadjusted)	−52.4 (−72.7 to −16.1)	0.013†
Δ NIRF (∗adjusted)	−48.1 (−69.4 to −12.0)	0.018†

Pearson Correlation Coefficients for Δ NIRF vs. IVUS-Derived Metrics (measured as Δ)
	rp Value	p Value
Δ NIRF vs. Δ TAV	0.50	0.006‡
Δ NIRF vs. Δ PAV	0.49	0.030†
Δ NIRF vs. Δ PB	0.46	0.041†

CI = confidence interval; IVUS = intravascular ultrasound; PAV = percent atheroma volume; PB = plaque burden; rp = reflecting Pearson; TAV = total atheroma volume; other abbreviations as in Table 1.

^∗Adjusted for baseline cholesterol, baseline CRP, baseline minimal lumen area, and corresponding atheroma parameter, at baseline (6 weeks).

^†p < 0.05;

^‡p < 0.01.