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. 2020 Jul 1;5(7):649–661. doi: 10.1016/j.jacbts.2020.05.004

Figure 1.

Figure 1

Association of the PCSK9 R46L Variant With CAVS

Association of the PCSK9 R46L variant with calcific aortic valve stenosis in a meta-analysis of 10 cohorts totaling 12,059 cases and 541,081 control subjects. CAVS = calcific aortic valve stenosis; CI = confidence interval; EPIC = European Prospective Investigation into Cancer and Nutrition; GERA = Genetic Epidemiology Research on Aging study; MDCS = Malmo Diet and Cancer Study; OR = odds ratio.