Table 3.
Half maximal inhibitory concentrations, IC50 (μg/ml, ± SEM) of isolated compounds and extracts from the root and stem of D. crassifolium compared with praziquantel standard against S. haematobium eggs.
| Compound/Extract | IC50 ± SEM (μg/ml) | |
|---|---|---|
| Friedelan-3-one | 378.10 ± 0.23 | |
| β-Sitosterol/stigmasterol | 177.90 ± 0.10 | |
| Dichapetalin M | 191.00 ± 0.12 | |
| Dichapetalin A | 151.1 ± 0.21 | |
| Extracts | Root | Stem |
| Petroleum ether | 546.40 ± 0.06 | 443.70 ± 0.04 |
| EtOAc | 248.60 ± 0.10 | 638.00 ± 0.08 |
| MeOH | 566.30 ± 0.07 | 893.70 ± 0.08 |
| Praziquantel | 15.47 ± 0.06 | |