Table 1.
Characteristics of children initiated on the ketogenic diet.
Child one | Child two | Child three | |
---|---|---|---|
Sex,Age (years) | Male,2.5 years | Male,6.5 years | Male,10 years |
Seizure onset | 9 months | 2 years | 4.5 years |
Seizure type | Epileptic spasms, atonic seizures and myoclonic seizures | Atypical absence, atonic seizures, frequent episodes of non-convulsive status epilepticus | Tonic, atypical absence |
Frequency at time of initiation | Up to 15 clusters of spasms and 3-5 atonic seizures per day | 1–2 atonic seizures per day | 1–5 per day |
Etiology | Genetic-Trisomy 21 | Symptomatic- history of encephalitis at age of 2 years | Perinatal injury |
Antiseiziure medication at initiation of KD | levetiracetam, valproic acid, lamotrigine | valproic acid, lamotrigine, clonazepam, levetiracetam | valproic acid, lamotrigine, clonazepam |
Pre-KD EEG | Diffuse encephalopathy multifocal, generalized, and polyspikes; consistent with hypsarrhythmia pattern primarily in sleep with a relatively better waking record | Diffuse encephalopathy; multifocal spikes | Diffuse encephalopathy; slow spike-and-wave with multifocal spikes and four electroclinical tonic seizures out of sleep captured |
Family/parent characteristics | |||
• Caregivers level of education | University | Primary school | Primary school |
• Monthly household income | Above K5,000/$300 | K1,000‐ K5,000/ $52‐$300) | Below K1000/$52 |
• Members in household | Father, mother, two elder sisters | Father, mother, three elder brothers | Father, mother, two brothers |
• Family diet provider | Mother, sisters and nanny | Mother and elder brother | Mother |