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. 2020 Jul 3;14:100380. doi: 10.1016/j.ebr.2020.100380

Table 1.

Characteristics of children initiated on the ketogenic diet.

Child one Child two Child three
Sex,Age (years) Male,2.5 years Male,6.5 years Male,10 years
Seizure onset 9 months 2 years 4.5 years
Seizure type Epileptic spasms, atonic seizures and myoclonic seizures Atypical absence, atonic seizures, frequent episodes of non-convulsive status epilepticus Tonic, atypical absence
Frequency at time of initiation Up to 15 clusters of spasms and 3-5 atonic seizures per day 1–2 atonic seizures per day 1–5 per day
Etiology Genetic-Trisomy 21 Symptomatic- history of encephalitis at age of 2 years Perinatal injury
Antiseiziure medication at initiation of KD levetiracetam, valproic acid, lamotrigine valproic acid, lamotrigine, clonazepam, levetiracetam valproic acid, lamotrigine, clonazepam
Pre-KD EEG Diffuse encephalopathy multifocal, generalized, and polyspikes; consistent with hypsarrhythmia pattern primarily in sleep with a relatively better waking record Diffuse encephalopathy; multifocal spikes Diffuse encephalopathy; slow spike-and-wave with multifocal spikes and four electroclinical tonic seizures out of sleep captured
Family/parent characteristics
 • Caregivers level of education University Primary school Primary school
 • Monthly household income Above K5,000/$300 K1,000‐ K5,000/ $52‐$300) Below K1000/$52
 • Members in household Father, mother, two elder sisters Father, mother, three elder brothers Father, mother, two brothers
 • Family diet provider Mother, sisters and nanny Mother and elder brother Mother