Figure 4.

GO enrichment map of m⁵C-modifed DEGs

Groups of upregulated genes with m⁵C gain (red), downregulated genes with m⁵C gain (pink), upregulated genes with m⁵C loss (blue), and downregulated genes with m⁵C loss (dark blue) are marked in the network (P < 0.01, hypergeometric test; for details, see Tables S3 and S4). The dots in the middle of the network with no functional labels represent genes that participate in multiple biological processes. GO, Gene Ontology; PPI, protein–protein interaction; DEG, differentially expressed gene.