Comparison of the receiver operating characteristic (ROC) curves of different models. (a, b) ROC curves of the different models in the training and validation cohorts. The clinicoradiomic model demonstrated the best discriminating ability amongst these models, with an AUC of 0.857 in the training cohort and an AUC of 0.819 in the validation cohort. (c, d) Radiomic signature histogram of the training and validation cohorts. The red bar shows the sample with brain invasion, and the blue bar shows the sample without brain invasion. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)