Table 1. Real-Life Costs During the FaMRIsc Trial by Group, Age, and Density.
| Characteristic | No. of breast cancersa | Life-years at risk | Costs, € (US $) | |
|---|---|---|---|---|
| Screening | Additional investigation | |||
| MRI group by age | ||||
| <50 y | 18 | 2106 | 740 188 (834 254.79) | 171 054 (192 792.40) |
| ≥50 y | 23 | 1112 | 357 578 (403 020.80) | 59 281 (66 814.73) |
| Total | 41b | 3218 | 1 097 766 (1 237 275.59) | 230 335 (259 607.12) |
| Mx group by age | ||||
| <50 y | 8 | 2099 | 341 568 (384 976.17) | 87 576 (98 705.60) |
| ≥50 y | 7 | 1215 | 178 692 (201 401.07) | 31 266 (35 239.44) |
| Total | 15 | 3314 | 520 260 (586 377.24) | 118 842 (133 945.04) |
| MRI group and registration MRI protocol by density category | ||||
| BI-RADS density A-C (0%-75%) | 38 | 2743 | 939 818 (1 059 254.77) | 184 004 (207 388.15) |
| BI-RADS density D (>75%) | 5 | 507 | 176 580 (199 020.67) | 52 750 (59 453.73) |
| Total | 43b | 3249 | 1 116 397 (1 258 274.31) | 236 754 (266 841.88) |
| Mx group and registration Mx protocol by density category | ||||
| BI-RADS A-C | 17 | 3648 | 567 145 (639 220.62) | 120 408 (135 710.05) |
| BI-RADS D | 6 | 659 | 105 386 (118 778.98) | 42 227 (47 593.42) |
| Total | 23 | 4308 | 672 531 (757 999.60) | 162 635 (183 303.47) |
Abbreviations: BI-RADS, Breast Imaging Reporting and Data System Atlas; FaMRIsc, Familial MRI Screening; MRI, magnetic resonance imaging; Mx, mammography.
a
Breast cancers include invasive breast cancers and ductal carcinoma in situ.
b
One additional cancer was added in this article, which was excluded in the previous article.9 This was an interval cancer between a mammogram and MRI in the first screening round in the MRI group.