Table 3:
Overview of the baseline clinical variables, clinical examination, hospital evaluations and outcomes in a cohort of post-cardiac arrest (n=53) grouped based on presence of BSP on EEG and outcomes within the group of patients with BSP. Data presented as average (IQR) or N/N(%) based on all available data points. (CA: cardiac arrest, OHCA: out-of-hospital cardiac arrest, ROSC: return of spontaneous circulation, TTM: targeted temperature management, SSEP: somatosensory evoked potential, NSE: neuron specific enolase, WLST: withdrawal of life sustaining therapy, CPC: cerebral performance categories).
| Total n=53 | Patients without BSP (n=36) | Patients with BSP | |||
|---|---|---|---|---|---|
| All (n=17) | Unfavorable Outcome (n=14) | Favorable outcome (n=3) | |||
| Baseline characteristics | age (at the time of CA) | 57.3 (47.25-68) | 62.82 (53-78) | 65.36 (53-79.5) | 51 (45-60.5) |
| sex, male | 24/36 (67%) | 13/17 (76%) | 10/14 (71%) | 3/3 (100%) | |
| setting, OHCA | 19/36 (53%) | 13/17 (76%) | 10/14 (71%) | 3/3 (100%) | |
| initial rhythm, shockable^ | 13/29 (45%) | 7/14 (50%) | 4/11 (36%) | 3/3 (100%) | |
| Witnessed^ | 34/36 (94%) | 14/16 (87.5%) | 11/13 (85%) | 3/3 (100%) | |
| ROSC (minutes)^ | 23.8 (9-35) | 22.75 (13.75-34.25) | 24.64 (15.25-34.75) | 9.5 (6.75-12.25) | |
| TTM, target temp | 5 (not cooled), 3 (33C), 1 (35.5C), 26 (36C), 1 (n/a) | 6 (33C), 1 (34.5C), 9 (36C), 1 (n/a) | 5 (33C), 1 (34.5C), 7 (36C), 1 (n/a) | 1 (33C), 2 (36C) | |
| length of ICU stay (days) | 23.5 (11.75-25.5) | 12.7 (7-19) | 11.29 (4.75-15.5) | 19.3 (18.5-20) | |
| Exam after rewarming/at 72 hours | pupillary reflex (present)^ | 31/35 (88%) | 12/17 (70%) | 9/12 (65%) | 3/3 (100%) |
| corneal reflex (present)^ | 6/12 (50%) | 11/14 (78%) | 8/12 (66%) | 3/3 (100%) | |
| motor response to pain (better than reflexive) | 19/36 (53%) | 3/17 (18%) | 1/14 (7%) | 2/3 (67%) | |
| Prognostic tests | SSEP, N20 absent^ | 2/13 (15%) | 3/8 (38%) | 3/7 (43%) | 0/1 (0%) |
| NSE > 33 ug/L^ | 6/23 (26%) | 7/13 (54%) | 7/12 (58%) | 0/1 (0%) | |
| MRI, abnormal^ | 10/25 (40%) | 4/7 (57%) | 4/5 (80%) | 0/2 (0%) | |
| outcomes | Died | 18/36 (50%) | 13/17 (76%) | 13/17 (76%) | n/a |
| Died after WLST | 13/18 (72%) | 11/13 (85%) | 11/13 (85%) | n/a | |
| Neurological reason for WLST | 10/13 (77%) | 9/11 (82%) | 9/11 (82%) | n/a | |
| Favorable outcome (CPC 1-2) | 7/36 (19%) | 3/17 (18%) | n/a | 3/3 (100%) | |
^
Data not available for all patients.