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. Author manuscript; available in PMC: 2020 Oct 8.
Published in final edited form as: Ann Emerg Med. 2019 Nov 13;76(4):470–485. doi: 10.1016/j.annemergmed.2019.09.001

Figure 2.

Figure 2.

Consensus anticoagulation reversal or replacement decision tree.* *Refer to Table 2 for anticoagulant characteristics and Table 3 for dosing of reversal and replacement agents. AT, Antithrombin; INR, international normalized ratio; PCC, prothrombin complex concentrate; vit K, vitamin K; FFP, fresh frozen plasma. †Based on last dose inclusion criteria used for clinical studies. ‡FDA approved for bleeding only (not emergency surgery/urgent procedure). §Not FDA approved. ‖If tier 1 not available. Includes 4-factor PCC (preferred), 3-factor PCC, and activated PCC.