TABLE 1.
Demographics and enrollment laboratory values for the longitudinal cohort
| FT females n = 200 | Frequent FT females n = 114 | HI females n = 92 | FT males n = 200 | Deferred males n = 33 | HI males n = 136 | ||
|---|---|---|---|---|---|---|---|
| White race | n (Col %) | 153 (75.5%) | 110 (96.5%) | 86 (93.5%) | 165 (82.5%) | 32 (97.0%) | 121 (89.0%) |
| Black race | n (Col %) | 17 (8.5%) | 1 (0.9%) | 1 (1.1%) | 13 (6.5%) | 0 (0.0%) | 0 (0.0%) |
| Asian/other/missing race | n (Col %) | 21 (10.5%) | 1 (0.9%) | 2 (2.2%) | 16 (8.0%) | 1 (3.0%) | 10 (7.4%) |
| Hispanic ethnicity | n (Col %) | 9 (4.5%) | 2 (1.8%) | 3 (3.3%) | 6 (3.0%) | 0 (0.0%) | 5 (3.7%) |
| Age (years) | Mean | 35.9 | 48.2 | 54.7 | 39.2 | 59.2 | 54.9 |
| Weight (lbs) | Mean | 158.9 | 166.3 | 155.6 | 198.9 | 186.4 | 179.9 |
| Body mass index | Mean | 26.5 | 27.7 | 26.4 | 27.7 | 26.7 | 26.6 |
| Any iron supplement | n (%) | 76 (39.2%) | 55 (48.2%) | 63 (68.5%) | 49 (24.5%) | 11 (33.3%) | 49 (36.3%) |
| Iron daily | n (%) | 45 (23.2%) | 35 (30.7%) | 53 (57.6%) | 33 (16.5%) | 8 (24.2%) | 36 (26.7%) |
| Iron at least weekly (<Daily) | n (%) | 31 (16.0%) | 20 (17.5%) | 10 (10.9%) | 16 (8.0%) | 3 (9.1%) | 13 (9.6%) |
| No iron or <weekly | n (%) | 118 (60.8%) | 59 (51.8%) | 29 (31.5%) | 151 (75.5%) | 22 (66.7%) | 86 (63.7%) |
| Any smoking - ever | n (%) | 72 (36.0%) | 48 (42.1%) | 38 (41.3%) | 78 (39.0%) | 15 (45.5%) | 54 (39.7%) |
| Any smoking - last 90 days | n (%) | 40 (20.0%) | 11 (9.6%) | 12 (13.0%) | 33 (16.5%) | 1 (3.0%) | 10 (7.4%) |
| Menstruating | n (%) | 149 (74.9%) | 60 (52.6%) | 26 (28.3%) | - | - | - |
| # Study donations | Mean | 2.19 | 5.04 | 7.90 | 3.08 | 6.88 | 7.84 |
| Any Hgb deferral | n (%) | 37 (18.5) | 48 (42.1) | 0 (0.0) | 2 (1.0) | 32 (97.0) | 0 (0.0) |
| Hemoglobin (g/dL) | Mean | 13.4 | 13.5 | 13.8 | 15.0 | 13.3 | 14.5 |
| Ferritin (ng/mL) | Mean | 44.7 | 62.4 | 26.0 | 140.9 | 13.0 | 28.4 |
| sTfR (μg/mL) | Mean | 2.8 | 2.9 | 3.3 | 2.9 | 4.5 | 3.5 |
| log(sTfR/ferritin) | Mean | 1.9 | 1.8 | 2.2 | 1.4 | 2.6 | 2.2 |
| Ferritin <12 ng/mL | n (%) | 18 (9.0%) | 3 (2.6%) | 16 (17.4%) | 0 (0.0%) | 20 (60.6%) | 23 (16.9%) |
| log(sTfR/ferritin)≥2.07 | n (%) | 59 (29.5%) | 23 (20.2%) | 59 (64.1%) | 4 (2.0%) | 31 (93.9%) | 82 (60.3%) |
| CHr (pg) | Mean | 32.4 | 33.1 | 32.5 | 33.2 | 30.6 | 32.4 |
| Percent low CHr | Mean | 7.2 | 4.7 | 5.8 | 4.9 | 20.7 | 7.2 |