Table 5.

US Multi-Society Task Force Recommendations for Post-Colonoscopy Follow-Up in Average-Risk Adults With Serrated Polyps^a

Baseline colonoscopy finding	Recommended interval for surveillance colonoscopy	Strength of recommendation	Quality of evidence
≤20 HPs in rectum or sigmoid colon <10 mm	10 yb	Strong	Moderate
≤20 HPs proximal to sigmoid colon <10 mm	10 y	Weak	Very low
1–2 SSPs <10 mm	5–10 y	Weak	Very low
3–4 SSPs <10 mm	3–5 y	Weak	Very low
5–10 SSPs <10 mm	3 y	Weak	Very low
SSP ≥10 mm	3 y	Weak	Very low
SSP with dysplasiae	3 y	Weak	Very low
HP ≥10 mm	3–5 yc	Weak	Very low
TSA	3 y	Weak	Very low
Piecemeal resection of SSP ≥20 mm	6 mo	Strong	Moderated

^aAll recommendations assume examination complete to cecum with bowel preparation adequate to detect lesions >5 mm in size; recommendations do not apply to individuals with a hereditary CRC syndrome, personal history of inflammatory bowel disease, personal history of hereditary cancer syndrome, serrated polyposis, or malignant polyp, personal history of CRC, or family history of CRC, and must be judiciously applied to individuals with a personal or family history of CRC, favoring the shortest indicated interval based on either history or polyp findings.

^bFollow-up may be with colonoscopy or other screening modality for average risk individuals.

^cA 3-year follow-up interval is favored if concern about consistency in distinction between SSP and HP locally, bowel preparation, or complete excision, whereas a 5-year interval is favored if low concerns for consistency in distinction between SSP and HP locally, adequate bowel preparation, and confident complete excision.

^dSee US Multi-Society Task Force recommendations for endoscopic removal of colorectal lesions.⁶⁹

^eAssumes high confidence of complete resection.