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. Author manuscript; available in PMC: 2020 Jul 31.
Published in final edited form as: Muscle Nerve. 2020 Jan 21;61(3):416–424. doi: 10.1002/mus.26798

FIGURE 5.

FIGURE 5

Force measurements during the fatigue protocol consisting of 80 contractions performed at 40 Hz (1.5 seconds on and 6 seconds off) in 12-month-old WT (n = 18) and Neb-cKO mice (n = 17). A, Representative force traces of the plantar flexor muscles recorded during the fatigue protocol in WT mice (top) and Neb-cKO mice (bottom). B, Plantar flexor muscles specific force production during the fatigue protocol. C, Mean specific force of the plantar flexor muscles during the whole fatigue protocol. D, Fatigue index calculated from the ratio between the last five and the first five contractions of the fatigue protocol. Values are mean ± SEM. ***P <0 .001, significantly different from WT mice. Neb-cKO, conditional nebulin knockout; WT, wildtype