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. Author manuscript; available in PMC: 2021 Jul 15.
Published in final edited form as: Org Biomol Chem. 2020 Jul 15;18(27):5174–5182. doi: 10.1039/d0ob00506a

Table 2:

Comparison of Kd values with PrOF NMR and SPR using acetylated histones.

Histone Peptide Literature Value (μM) PrOF NMR Kd (μM) GST-BPTF SPR Kd (μM)
H4 K16ac 99 ± 7 38
300 ± 50 39 		190 150 ± 67
H2AZ.I K4ac,K11ac 780 ± 64 39 720 710 ± 140
H4 K5ac,K8ac,K12ac,K16ac 124 40 70 65 ± 18