Table 2.
The association between SNP and memory change after dependence
| Gene | Variable/ID | No change (n = 215) | Reduced (n = 586) | Pa | OR, 95% CI | Pb | Exp(B), 95% CI | ||
|---|---|---|---|---|---|---|---|---|---|
| Number | Percent | Number | Percent | ||||||
| rs1611114 | 0.007n | 0.005n | |||||||
| TT | 111 | 51.6 | 231 | 39.4 | 0.002 | 0.610, 0.445–0.835 | 0.002 | 0.607, 0.440–0.837 | |
| TC | 79 | 36.7 | 281 | 48.0 | 0.005n | 1.586, 1.150–2.187 | 0.002 | 1.673, 1.204–2.325 | |
| CC | 25 | 11.6 | 74 | 12.6 | 0.703 | 1.098, 0.678–1.780 | 0.956 | 0.986, 0.600–1.620 | |
| T | 301 | 70.0 | 743 | 63.4 | 0.014n | 0.742, 0.585–0.942 | |||
| C | 129 | 30.0 | 429 | 36.6 | |||||
Pa: Genotypic and allele frequency difference assessment by chi-square test
Pb: Genotypic and allele frequency difference assessment by binary logistic regression
n: The result was not significant after Bonferroni’s correction