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. 2020 Jul 30;20:353. doi: 10.1186/s12872-020-01634-7

Table 2.

Risk factors associated with baPWV in mixed models

All DM Non-DM
beta (95%CI) P value beta (95%CI) P value beta (95%CI) P value
Age (year) 12.69 (12.44,12.92) < 0.001* 12.47 (12.20,12.74) < 0.001* 14.64 (13.78,15.48) < 0.001*
Postprandial 2 h-glucose (mmol/L) 10.46 (9.24,11.68) < 0.001* 10.38 (8.71,12.05) < 0.001* 6.42 (3.81,9.04) < 0.001*
Systolic blood pressure (mmHg) 5.95 (5.93,6.18) < 0.001* 5.98 (5.74,6.21) < 0.001* 5.76 (5.14,6.38) < 0.001*
Hypertension NA NA 25.80 (18.26,33.33) < 0.001* NA NA
Platelet counts (109/L, per SD) NA NA 10.77 (5.91,20.63) < 0.001* NA NA
Mean corpuscular volume (fL) NA NA 0.04(−0.53,0.61) 0.891 NA NA
Coronary heart disease NA NA −2.48(−14.03,9.07) 0.673 NA NA
Interaction term: DM × PLTa 0.177 (0.067, 0.287) 0.0016* NA NA NA NA

Only variables which were significantly associated with baPWV in lasso regression were included in mixed models

aIn all participants, interaction terms of diabetes (DM) and platelet counts (PLT) were added in mixed models, adjusting for age, Postprandial 2 h-glucose, Systolic blood pressure

*P value is significant after Bofferoni correction