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. 2020 Jul 31;26(4):459–473. doi: 10.1007/s13365-020-00868-7

Table 1.

Representative mammalian coronaviruses and their dominant cell receptors or attachment factors

Virus Abbreviation Cell receptor or attachment factor
Genus: Alphacoronaviruses
  Human coronavirus 229E HCoV-229E APN (CD13)
  Human coronavirus NL63 HCoV-NL63 ACE2
  Alphacoronavirus 1 species:
    Transmissible gastroenteritis virus TGEV APN (CD13)
    Feline coronavirus type 1 FCoV-1
    Feline infectious perionitis virus FIPV APN (CD13)
    Canine coronavirus CCoV APN (CD13)
  Porcine epidemic diarrhea virus PEDV APN (CD13)
  Diverse bat coronaviruses
Genus: Betacoronaviruses
  Human coronavirus HKU1 HCoV-HKU1 N-Acetyl-9-O-acetylneuraminic acid (9-O-acetylsialic acid)
  Betacoronavirus 1 species:
    Human coronavirus OC43 HCoV-OC43 N-Acetyl-9-O-acetylneuraminic acid (9-O-acetylsialic acid)
    Bovine coronavirus BCoV N-Acetyl-9-O-acetylneuraminic acid (9-O-acetylsialic acid)
    Equine coronavirus EqCoV 9-O-Acetylsialic acid determinant?
    Porcine hemagglutinating encephalomyelitis virus PHEV 9-O-Acetylsialic acid determinant?
    Dromedary camel coronavirus HKU23 DcCoV HKU23
    Severe acute respiratory syndrome-related coronavirus species:
    Human SARS coronavirus SARS-CoV ACE2, also L-SIGN (CD209L)
    Human SARS coronavirus-2 SAR-CoV-2 ACE2
    SARS-related Rhinolophus bat coronavirus Rp3 SARSr-Rh-BatCoV Rp3
  Middle East respiratory syndrome-related coronavirus MERS-CoV DPP4 (CD26)
  Murine coronavirus species:
    Mouse hepatitis virus MHV CEACAM1, also L-SIGN (CD209L), also 4-O- or 9-O-acetylsialic acid
    Rat coronavirus RCoV
  Diverse bat coronaviruses
Genus: Deltacoronaviruses
  Porcine deltacoronavirus PDCoV APN (CD13)

ACE2 angiotensin-converting enzyme 2, APN aminopeptidase N, DPP4 dipeptidyl peptidase 4