Table 3.

Association between demographic and clinical factors with drug resistance

		Any resistance			Rifampin, MDR-TB
Variable	Level	Pan-susceptible, n = 59 (%)	Resistant, n = 11 (%)	P-value	Pan-susceptible, n = 59 (%)	Resistant, n = 8 (%)	P-value
Demographic
Sex	Female	24 (41%)	4 (36%)	0.789	24 (41%)	2 (25%)	0.393
	Male	35 (59%)	7 (64%)		35 (59%)	6 (75%)
Age groups	Adults (> 17 y)	55 (93%)	10 (91%)	0.785	55 (93%)	7 (88%)	0.563
	Children = < 16 y	4 (7%)	1 (9%)		4 (7%)	1 (12%)
TB/DOTS Facilities	Folang	1 (2%)	0	0.958	1 (2%)	0	0.856
	Kalafong	21 (36%)	5 (45%)		21 (36%)	4 (50%)
	Mamelodi	9 (15%)	1 (9%)		9 (15%)	0
	Potchefstroom	4 (7%)	0		4 (7%)	0
	Pretoria West	3 (5%)	1 (9%)		3 (5%)	1 (12%)
	Skinner	2 (3%)	0		2 (3%)	0
	Steve Biko	11 (19%)	3 (27%)		11 (19%)	2 (50)
	Tshwane District Hosp.	8 (14%)	1 (9%)		8 (14%)	1 (13%)
Clinical
Genotypes	Beijing	22 (37%)	3 (27%)	0.737	22 (37%)	1 (12%)	0.350
	Cas_KILI	4 (7%)	0		4 (7%)	0
	EAI1_SOM	1 (2%)	1 (9%)		1 (2%)	1 (12%)
	LAM11_ZWE	2 (3%)	0		2 (3%)	0
	LAM3	4 (7%)	0		4 (7%)	0
	LAM4	2 (3%)	1 (9%)		2 (3%)	1 (12%)
	LAM9	2 (3%)	1 (9%)		2 (3%)	1 (12%)
	S	3 (5%)	0		3 (5%)	0
	T1	3 (5%)	0		3 (5%)	0
	X1	4 (7%)	1 (9%)		4 (7%)	0
	X3	2 (3%)	1 (9%)		2 (3%)	1 (12%)
Unclustered	Orphan/X2	10 (17%	3 (27%)	0.419	10 (17%)	3 (38%)	0.168
Disease Site	Disseminated	4 (7%)	0	0.134	4 (7%)	0	0.036
	Lymph nodes	16 (27%)	4 (36%)		16 (27%)	4 (38%)
	Meninges	4 (7%)	1 (9%)		4 (7%)	0
	EPTB/PTB	3 (5%)	0		3 (5%)	0
	Pericardium	1 (2%)	0		1 (2%)	0
	Peritoneum	5 (8%)	0		5 (8%)	0
	Pleura	19 (32%)	1 (9%)		19 (32%)	0
	Genitourinary	2 (3%)	0		2 (3%)	0
	Cutaneous TB	5 (8%)	5 (45%)		5 (8%)	5 (63%)

MDR-TB Multidrug resistant tuberculosis; EPTB Extra-pulmonary TB; PTB Pulmonary TB