Table 4.

Neuropsychiatric Assessments

	Patients						Controls
	N = 39		AN-BP N = 19		AN-R N = 20		N = 10
	Baseline	Post	Baseline	Post	Baseline	Post	Baseline	Post
Wide Range Achievement Test (W-RAT 4) Word Reading Subtest, Mean + SD	62.3 + 4.4		62.4 + 4.5		62.3 + 4.5		64.0 + 4.0
Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) Total Score, Mean + SD	94.1 + 12.6	97.1 + 10.6*	97.2 + 11.4	98.4 + 11.4	91.1 + 13.3**	95.8 + 10.0*	101.6 + 11.7	105.3 + 8.8
Beck Depression Inventory (BDI-II) Total Score, Median (IQR)	35 (30, 42)	20 (13, 28)*	33 (30, 39)	20 (15, 29)*	38 (29.5, 45)	19.5 (10, 26)*	3.5 (1, 5)	1 (0, 3)
Beck Anxiety Inventory (BAI) Total Score, Median (IQR)	25 (17, 33)	19 (12, 24)*	23 (14, 31)	19 (10, 21)*	29 (18.5, 40)	17.5 (14, 26.5)*	3 (1, 4)	1.5 (0, 4)
Trail Making Test, Part B Score, Mean + SD	34.7 + 10.5	39.5 + 10.5	37.4 + 8.6	40.8 + 10.1	32.2 + 11.7	38.2 + 10.9*	40.4 + 9.2	44.2 + 6.1
Obsessive Compulsive Inventory – Revised (OCI-R), Median (IQR)
Checking	3 (2, 4)	2 (0, 3)*	3 (2, 6)	1 (0, 4) *	2 (1.5, 4)	2 (0.5, 2.5) *	0 (0, 0)	0 (0, 0)
Hoarding	4 (1, 6)	2 (0, 4)*	3 (0, 6)	2 (0, 6)	5 (1, 6)	2 (0, 2.5)*	1.5 (0, 3)	1 (0, 3)
Neutralizing	3 (1, 7)	1 (0, 6)*	1 (0, 6)	1 (0, 6)	5 (2, 7.5)	1.5 (0.5, 3.5)*	0 (0, 0)	0 (0, 0)
Obsessing	7 (3, 10)	3 (2, 7)*	6 (2, 10)	4 (1, 7)*	7 (3, 9.5)	3 (2, 7.5)*	1 (0, 3)	0 (0, 2)
Ordering	7 (5, 11)	6 (4, 9)	8 (5, 11)	7 (3, 9)	7 (4, 11)	6 (4, 11)	1.5 (0, 3)	2.5 (0, 3)
Washing	2 (0, 7)	1 (0, 4)*	2 (0, 7)	1 (0, 6)	1.5 (1, 7)	1.5 (0, 3.5)	0 (0, 0)	0 (0, 0)
Leptin Level (ng/mL), N (%)
< 0.4	31 (79)	19 (49)	16 (84)	10 (53)	15 (75)	9 (45)
0.4–1.0	7 (18)	10 (26)	3 (16)	6 (32)	4 (20)	7 (35)
> 1.0	1 (3)	7 (18)	0 (0)	2 (11)	1 (5)	2 (10)
< 6.0							4 (40)
6.0–10.0							2 (20)
> 11.0							3 (30)
Increase in Leptin Level, N (%)	14 (36)		6 (32)		8 (40)

*P < 0.05 change from baseline

**P < 0.05 relative to baseline of controls