Table 2.

Association between delirium during the intensive care unit and subsequent neuropsychiatric disorders

	Risk ratio (95% confidence interval)a
Outcome	Crude	Adjustedb
Any neuropsychiatric disorder	1.36 (1.20–1.54)	1.14 (0.98–1.33)
Depressive	1.45 (1.20–1.74)	1.16 (0.92–1.45)
Anxiety	1.31 (1.08–1.60)	1.16 (0.92–1.47)
Trauma-and-stressor related	1.14 (0.79–1.63)	0.82 (0.53–1.28)
Neurocognitive	2.19 (1.57–3.09)	1.59 (1.08–2.35)

^aReference group is “never” had ICU delirium

^bAdjusted for age, sex, ICU admission reason (medical, surgical, neurological, trauma), APACHE II score, Charlson Comorbidity score, Glasgow Coma Scale, transfer delay, ≥ 24 h, invasive mechanical ventilation (yes/no), continuous renal replacement therapy (yes/no), and vasoactive medications (yes/no), ≥ 20 ICU beds, teaching hospital (yes/no), ICU length of stay (categorized as < 7 days vs. ≥ 7 days), and last SOFA score