Table 7.

Medication used by patients

Study	Group	Medication
		Carbamazepine	Gabapentin	Other medications
		N	N	N
Wu et al. [27]	BT-A	19	7	Opioids
				1
	Placebo	17	9	2
Shehata et al. [28]	BT-A	All patients had been treated with drugs known to improve TN, 11 patients were on carbamazepine (600 to 1400 mg) either alone (n = 2), in combination with gabapentine (400 to 1200 mg) (n = 5) or on triple therapy with baclofen (30 to 75 mg) (n = 4). Nine patients were on oxcarbazepine (900 to 1800 mg) either alone (n = 2) or in combination with gabapentine (n = 5).
	Placebo
Zúñiga et al. [29]	BT-A	19	1	Amitriptyline
				0
	Placebo	12	3	2
Zhang et al. [30]	BT-A (25 U)	At baseline, patients usually received medications (e.g. carbamazepine, gabapentin or opioids) to alleviate their pain. These medications remained unchanged during the course of the study. There were no new analgesic therapies at any time during the baseline or placebo run-in period.
	BT-A (75 U)
	Placebo

N = number; U = units per ml of solution; BT-A = botulinum toxin type A; TN = trigeminal neuralgia.