Table 4.
Cox Proportional Hazard (1) and Fine and Gray Competing Risk (2) Models of the predictors of post-stroke hip fracture risk among postmenopausal stroke survivors in the Women’s Health Initiative (1993–2010).
Variable | Model 1 Adjusted HR | 95% CI | Model 2 Adjusted HR | 95% CI |
---|---|---|---|---|
GOS Category | ||||
Good Recovery | Reference | - | Reference | - |
Moderate Disability | 1.07 | 0.67–1.70 | 1.04 | 0.66–1.64 |
Severe Disability | 2.10* | 1.37–3.23 | 1.51 | 0.98–2.33 |
Age, years | 1.06* | 1.02–1.10 | 1.03 | 1.00–1.06 |
Race/ethnicity | ||||
White | Reference | - | Reference | - |
Non-White | 0.41* | 0.18–0.96 | 0.42* | 0.18–0.99 |
FRAX without BMD Risk Score | ||||
<3%, low risk | Reference | - | Reference | - |
≥3%, high risk | 1.87* | 1.18–2.98 | 2.05* | 1.25–3.36 |
Calcium/Osteoporosis medication use | 1.26 | 0.85–1.86 | 1.22 | 0.82–1.80 |
Depressive Symptoms Score (CES-D) | 0.92 | 0.14–6.03 | 0.80 | 0.14–4.60 |
History of Diabetes | 0.97 | 0.60–1.58 | 0.97 | 0.60–1.58 |
Smoking Status | ||||
Never | Reference | - | Reference | - |
Former | 1.10 | 0.76–1.61 | 1.07 | 0.73–1.56 |
Current | 1.28 | 0.61–2.67 | 1.06 | 0.52–2.16 |
Model 1: Cox Proportional Hazard Model
Model 2: Fine and Gray Competing Risk Model
HR: Hazards Ratio; CI: Confidence Interval
GOS: Glasgow Outcome Scale; FRAX: Fracture Risk Assessment Tool; BMD: bone mineral density; CES-D: Center for Epidemiological Studies Depression Scale
p<0.05