Table 1. Patient information of samples used in the comprehensive proteomic experiments.
| Sample | Age (years old) | FIGO stage | Lesion size (mm) | Depth of invasion | Immunohistochemical diagnosis | Chief complaint | TCT | HPV |
|---|---|---|---|---|---|---|---|---|
| Ctrl-1 | 49 | Normal | Routine physical | − | − | |||
| Ctrl-2 | 44 | Normal | Routine physical | − | − | |||
| Ctrl-3 | 40 | Normal | Routine physical | − | − | |||
| AIS-1 | 36 | 0 | 2.3 | Ki67(70%+), P16(+), ER(−) | Cervical lesions | ASC-H | + | |
| AIS-2 | 32 | 0 | 2 | Ki67(90%+), P16(+), ER(−) | Vaginal bleeding after intercourse | + | + | |
| AIS-3 | 43 | 0 | <7 | Ki67(50%+), P16(+), ER(+) | Cervical lesions | − | + | |
| EA-1 | 54 | II A1 | 12 | >1/3 & <2/3 | Ki67(60%+), P16(+), ER(−) | Vaginal bleeding after menopause | NK | NK |
| EA-2 | 37 | I B2 | ≤20 | >1/3 & <2/3 | Ki67(2%+), P16(++), ER(+) | Menstrual disorder and abnormal leukorrhea | ASC-US | + |
| EA-3 | 34 | II A1 | 30 | >1/3 & <2/3 | Ki67(80%+), P16(−), ER(−) | Vaginal bleeding after intercourse | HSIL | + |
Note:
Ctrl indicates the normal cervix; AIS indicates adenocarcinoms in situ of the cervical; EA indicates endocervical adenocarcinoma; TCT, Thinprep cytology test; HPV, human papillomavirus; −, negative; +, positive; NK, not known; ASC-H, atypical squamous cells: cannot exclude high-grade squamous intraepithelial lesion; ASC-US, atypical squamous cells of undetermined significance; HSIL, high-grade squamous intraepithelial lesions.