Table 2.

Effect of TRYP and TRYP-Ox on the top ranked molecular targets.

Compound	JNK1	JNK3	AChE inhibitionIC30 (µM)
	Kd (µM)a
TRYP	23.0	No binding	4.2 ± 1.2
(E/Z)-TRYP-Ox	0.150	0.275	12.0 ± 3.9

^aPreviously reported binding affinity (Schepetkin et al., 2019).