Table 1.
Pt | Gender/age (yr) | Body distribution | Isolated or combined | Etiology | Pre-operative medical treatment | Post-operative medical treatment |
---|---|---|---|---|---|---|
1 | M/8 | Generalized | Combined (spasticity) | Mitochondrial disorder | Gabapentin 100 mg; intrathecal baclofen 3 ug/hr | Unchanged |
2 | M/8 | Generalized | Isolated | Idiopathic | THP 20 mg | No |
3 | M/18 | Segmental | Isolated | Idiopathic | THP 24 mg; BTX | THP 24 mg |
4 | F/22 | Generalized | Isolated | ACTB mutation | THP 16 mg; tramadol 50 mg | THP 12 mg; clonazepam 1.5 mg; clozapine 18.75; BTX |
5 | F/32 | Segmental | Isolated | Idiopathic | Ibuprofen; BTX | No |
6 | M/9 | Generalized | Isolated | DYT-THAP1 | THP 21 mg; baclofen 12.5 mg | THP 11 mg |
7 | M/22 | Segmental | Isolated | TTPA | Vitamin E | Unchanged |
8 | M/47 | Generalized | Combined (spasticity) | Cerebral palsy | Antidepressants | Unchanged |
9 | M/53 | Segmental | Isolated | Idiopathic | Clonazepam 0.5 mg; BTX | BTX |
10 | F/65 | Segmental | Combined (parkinsonism) | Idiopathic | Pramipexole; L-dopa; Diazepam 5 mg; BTX | Pramipexole; L-Dopa |
11 | F/48 | Generalized | Isolated | ACTB mutation | THP 12 mg; clozapine 12.5 mg; oxazepam 10 mg; diclofenac; BTX antidepressant | THP 12 mg; clozapine 12.5 mg; antidepressant |
12 | F/63 | Segmental | Isolated | Idiopathic | Clonazepam 2.5 mg | Clonazepam 0.5 mg |
13 | M/62 | Segmental | Isolated | Idiopathic | BTX | Clonazepam 1.0 mg; BTX |
14 | F/8 | Generalized | Combined (spasticity) | Cerebral palsy | THP 1.5 mg; baclofen 12 mg; gabapentin 600 mg; clonazepam 0.5 mg | Unchanged |
15 | F/63 | Segmental | Isolated | Idiopathic | No | No |
ACTB: beta-actin gene; BTX: botulinum toxin injections; THP: trihexiphenidyl; TTPA α-tocopherol transfer protein – vitamin E.