Figure 1. Model human gut microbiomes replicate structure of communities affected by diarrhea-induced dysbiosis.
(A) Defined human gut communities. (B) Composition of healthy US human donor fecal microbiomes. (C) Principal coordinates analysis of defined and complete human gut microbiomes based on weighted UniFrac distance, % variance explained shown in parentheses. Ellipses show 95% confidence intervals. (D) Weighted UniFrac distance to indicated defined human model microbiomes of fecal samples from cholera patients at the end of diarrhea (left) and healthy human donors (right) *P<0.05, ****P<0.0001, Mann-Whitney U-test. Boxplots show inter-quartile range, whiskers minimum to maximum.