Table 13.
Blood exposure parameters for 37 following oral dosing to P. falciparum-infected SCID mice.
| Dose mg/kg | Blood Cmax μg/mL(μM) | Blood AUC23 h μg.h/mL (μM.h) |
|---|---|---|
| 10 | 0.194 (0.6) | 0.680 (2.10) |
| 50 | 2.52 (7.81) | 8.60 (26.7) |
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