Table 7.

The correlation between TNFAIP2 rs8126 polymorphism and gastric cancer (GC) prognosis in the subgroup analysis.

Parameters	Genotype	GC	Death	Median survival time (mean)	Univariate analysis		Multivariate analysis
					P-value	HR (95% CI)	P-value*	HR (95% CI)
rs8126		n = 287	n = 120
Gender
Male	TT	103	44	56.3b
	TC	79	32	79.0a	0.843	0.955 (0.606–1.506)	0.488	1.177 (0.743–1.864)
	CC	29	13	68.0a	0.961	1.016 (0.547–1.886)	0.795	1.087 (0.579–2.039)
	CC + TC vs. TT				0.892	0.972 (0.641–1.472)	0.499	1.156 (0.760–1.758)
	CC vs. TC + TT				0.912	1.034 (0.574–1.862)	0.948	1.020 (0.562–1.850)
Female	TT	34	14	50.4b
	TC	30	12	51.8b	0.943	1.029 (0.476–2.225)	0.762	1.132 (0.506–2.532)
	CC	12	5	54.3b	0.700	1.223 (0.439–3.405)	0.081	2.729 (0.883–8.431)
	CC + TC vs. TT				0.846	1.073 (0.529–2.177)	0.522	1.275 (0.606–2.679)
	CC vs. TC + TT				0.719	1.192 (0.457–3.112)	0.278	1.733 (0.641–4.681)
Age (years)		n = 287	n = 120
≥60	TT	65	29	58.0a
	TC	51	23	57.0a	0.925	1.027 (0.593–1.776)	0.506	1.210 (0.690–2.124)
	CC	20	7	58.9b	0.400	0.701 (0.307–1.603)	0.570	0.783 (0.336–1.823)
	CC + TC vs. TT				0.765	0.925 (0.555–1.543)	0.788	1.074 (0.638–1.809)
	CC vs. TC + TT				0.371	0.697 (0.317–1.536)	0.446	0.732 (0.329–1.632)
<60	TT	72	29	53.8b
	TC	58	21	79.0a	0.673	0.886 (0.505–1.554)	0.968	1.012 (0.570–1.797)
	CC	21	11	68.0a	0.332	1.410 (0.704–2.826)	0.147	1.690 (0.832–3.435)
	CC + TC vs. TT				0.961	1.013 (0.612–1.674)	0.501	1.192 (0.715–1.985)
	CC vs. TC + TT				0.224	1.501 (0.780–2.888)	0.152	1.628 (0.836–3.170)
H. pylori infection		n = 287	n = 120
Positive	TT	76	29	56.7b
	TC	56	23	79.0a	0.660	1.131 (0.654–1.956)	0.108	1.583 (0.904–2.772)
	CC	20	6	63.1b	0.437	0.705 (0.292–1.700)	0.549	0.760 (0.309–1.865)
	CC + TC vs. TT				0.999	1.000 (0.597–1.673)	0.294	1.329 (0.781–2.261)
	CC vs. TC + TT				0.338	0.661 (0.284–1.542)	0.345	0.662 (0.282–1.557)
Negative	TT	61	29	58.0a
	TC	53	21	54.1b	0.427	0.796 (0.454–1.397)	0.488	0.816 (0.460–1.450)
	CC	21	12	29.0a	0.361	1.369 (0.698–2.686)	0.101	1.792 (0.893–3.595)
	CC + TC vs. TT				0.779	0.931 (0.565–1.534)	0.902	0.969 (0.586–1.604)
	CC vs. TC + TT				0.196	1.516 (0.807–2.850)	0.080	1.794 (0.932–3.454)

^*Borrmann classification, TNM staging, lymph node metastasis, and depth of invasion were taken as covariables.

^aMedian survival time.

^bMean survival time.