TABLE E3.
Sociodemographic and clinical associations of inpatient admission among patients with HAE
| Variable | Not admitted | Inpatient admission | ||||||
|---|---|---|---|---|---|---|---|---|
| Weighted frequency | Prevalence (95% CI) | Weighted frequency | Prevalence (95% CI) | Crude OR (95% CI) | P | Adjusted OR* (95% CI) | P | |
| Sex | ||||||||
| Male | 3019 | 93.7 (91.2-96.2) | 204 | 6.3 (3.8-8.8) | 1.00 (reference) | — | 1.00 (reference) | — |
| Female | 5181 | 90.9 (87.5-94.3) | 519 | 9.1 (5.7-12.5) | 1.48 (0.87-2.54) | .27 | 2.34 (1.17-4.67) | .04 |
| Age (y) | ||||||||
| <18 | 1594 | 97.8 (96.1-99.5) | 36 | 2.2 (0.5-3.9) | 1.00 (reference) | — | 1.00 (reference) | — |
| 18-39 | 2976 | 91.4 (88.5-94.3) | 282 | 8.6 (5.7-11.5) | 4.23 (1.69-10.58) | .008 | 3.13 (1.13-8.70) | .07 |
| 40-59 | 2153 | 86.9 (81.1-92.8) | 324 | 13.1 (7.2-18.9) | 6.72 (2.76-16.37) | .0002 | 7.24 (2.84-18.45) | .0002 |
| 60+ | 1477 | 94.7 (89.5-99.9) | 83 | 5.3 (0.1-10.5) | 2.50 (0.73-8.65) | .27 | 1.16 (0.22-6.00) | .89 |
| Income | ||||||||
| <50th %’ile | 4166 | 91.0 (88.2-93.9) | 410 | 9.0 (6.1-11.8) | 1.37 (0.72-2.60) | .52 | † | † |
| >50th %’ile | 3915 | 93.3 (89.8-96.8) | 281 | 6.7 (3.2-10.2) | 1.00 (reference) | — | † | † |
| Insurance status | ||||||||
| Private | 3100 | 93.3 (90.9-95.8) | 221 | 6.7 (4.2-9.1) | 1.00 (reference) | — | 1.00 (reference) | — |
| Public | 4606 | 91.9 (88.2-95.6) | 406 | 8.1 (4.4-11.8) | 1.24 (0.69-2.23) | .007 | 1.58 (0.92-2.72) | .19 |
| Uninsured | 490 | 83.5 (76.2-90.8) | 92 | 16.5 (9.2-23.8) | 2.78 (1.47-5.25) | .68 | 3.16 (1.45-6.90) | .01 |
| Weekend admission | ||||||||
| No | 6025 | 92.1 (89.6-94.6) | 517 | 7.9 (5.4-10.4) | 1.00 (reference) | — | † | † |
| Yes | 2175 | 91.3 (88.0-94.7) | 206 | 8.7 (5.3-12.0) | 1.11 (0.79-1.56) | .69 | † | † |
| Hospital location | ||||||||
| Metropolitan | 6761 | 91.0 (87.9-94.0) | 672 | 9.0 (6.0-12.1) | 1.00 (reference) | — | 1.00 (reference) | — |
| Not metropolitan | 1440 | 96.5 (93.3-99.8) | 52 | 3.5 (0.2-6.7) | 0.36 (0.13-1.02) | .11 | 0.35 (0.13-0.95) | .09 |
| Region | ||||||||
| Northeast | 1614 | 90.8 (83.2-98.5) | 163 | 9.2 (1.5-16.8) | 1.00 (reference) | — | 1.00 (reference) | — |
| Midwest | 2149 | 92.4 (88.1-96.8) | 176 | 7.6 (3.2-11.9) | 0.81 (0.27-2.44) | .75 | 0.58 (0.22-1.49) | .42 |
| South | 2165 | 88.3 (84.1-92.4) | 287 | 11.7 (7.6-15.9) | 1.31 (0.48-3.57) | .69 | 0.79 (0.34-1.82) | .69 |
| West | 2272 | 95.9 (92.8-99.0) | 98 | 4.1 (1.0-7.2) | 0.42 (0.13-1.41) | .28 | 0.33 (0.12-0.96) | .09 |
| Hospital teaching status | ||||||||
| Nonteaching | 3785 | 93.2 (90.7-95.7) | 275 | 6.8 (4.3-9.3) | 1.00 (reference) | — | † | † |
| Teaching | 4415 | 90.8 (86.5-95.1) | 448 | 9.2 (4.9-13.5) | 1.40 (0.73-2.68) | .50 | † | † |
| Season | ||||||||
| Winter | 1820 | 91.9 (88.4-95.4) | 160 | 8.1 (4.6-11.6) | 1.15 (0.71-1.86) | .69 | † | † |
| Spring | 1909 | 92.8 (89.8-95.9) | 147 | 7.2 (4.1-10.2) | 1.00 (reference) | — | † | † |
| Summer | 2309 | 93.6 (91.0-96.3) | 157 | 6.4 (3.7-9.0) | 0.88 (0.54-1.43) | .69 | † | † |
| Autumn | 1885 | 91.4 (87.8-95.0) | 178 | 8.6 (5.0-12.2) | 1.22 (0.72-2.07) | .67 | † | † |
Bold text indicates that the P value was statistically significant.
*
Multivariable model was adjusted for sex, age, insurance status, hospital location, and region after stepwise variable selection.
†
The variable was not included in the final multivariable models.