Table 2.

SARS-CoV-2 proteins and human proteome interactive pathways

SARS-CoV-2 proteins	Human proteome interactive pathways
Nsp1	DNA replication
Nsp5, Nsp8, Nsp13, E	Epigenetic and gene expression regulators
Nsp6, Nsp7, Nsp10, Nsp13, Nsp15, Orf3a, E, Orf8	Vesicle trafficking
Spike	Lipid modification
Nsp8, N	RNA processing and regulation
Orf10	Ubiquitin ligases
Nsp8, Nsp13, N, Orf9b	Host signaling
Nsp9, Nsp15, Orf6	Nuclear transport machinery
Nsp1, Nsp13	Cytoskeleton
Nsp4, Nsp8, Orf9c	Mitochondria
Nsp9	Extracellular matrix

Source: Gordon et al. (2020)