Table 2.
Summary of in vivo tumour growth and lung metastasis of canine OS cell lines
| Cell line | % Tumour takea | Tumour latencyb (days) | Tumour growth (days)c | Spontaneous metastasis (%) |
|---|---|---|---|---|
| KOS-001 | 90% (9/10) | 151 ± 6 | 183 ± 14 | 0% (0/9) |
| KOS-002 | 0% (0/10) | NA | NA | NA |
| KOS-003 | 100% (10/10) | 35 ± 0 | 62 ± 0 | 100% (10/10) |
| KOS-004 | 90% (9/10) | 147 ± 3 | 162 ± 14 | 0% (0/9) |
a
Percent of mice that develop primary tumours following paraoseous injection of 2 million cells to Beige-SCID mice.
b
Median time (days) to tumour detection.
c
Median time (days) for tumour to grow to 1.5 cm in diameter.