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. 2020 Jul 29;8(1):e001101. doi: 10.1136/bmjdrc-2019-001101

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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miR-196b-5p expression increased in serum and kidney of patients with diabetic kidney disease (DKD). (A) Scatter plots of serum miR-196b-5p expression level in patients with diabetes mellitus (DM) with DKD (n=11) and without DKD (n=11). Each dot represents one patient. **p<0.01vs DM. (B) Correlation analysis of serum miR-196b-5p with albumin-to-creatinine ratio (UACR). The Spearman’s correlation coefficient (R) is given. (C) Representative image of periodic acid-Schiff (PAS) staining and Masson’s trichrome staining (MTS) for interstitial injury and fibrosis detection and representative image of miR-196b-5p staining of patients with or without DKD assessed by in situ hybridization. Scale bar, 100 µm. miRNA, micro RNA.