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. 2020 Jul 31;15(7):e0237075. doi: 10.1371/journal.pone.0237075

Table 2. Univariate and multivariate Cox regression analyses on patient survivals.

Univariate Multivariate
Hazard ratio 95%CI p value Hazard ratio 95%CI p value
Sex
 Female Reference Reference
 Male 4.44 (0.97–20.25) 0.055
Age 1.08 (1.05–1.12) <0.001** 1.07 (1.01–1.13) 0.013*
Crescents
 0 Reference Reference Reference Reference
 1 3.93 (1.18–13.07) 0.025* 5.75 (1.14–29.05) 0.034*
Albumin 0.23 (0.11–0.50) <0.001** 0.38 (0.05–3.09) 0.367
Total protein 0.46 (0.28–0.75) 0.002** 0.85 (0.22–3.22) 0.809
Low-density lipoprotein 0.99 (0.97–1.00) 0.154
High-density lipoprotein 0.95 (0.91–0.99) 0.009** 0.94 (0.90–0.99) 0.026*
Daily urine protein 1.14 (1.01–1.29) 0.038* 0.97 (0.78–1.20) 0.771
Urinary protein/creatinine ratio 1.07 (1.02–1.12) 0.003**
IgG 1.00 (1.00–1.00) 0.398
IgM 0.98 (0.96–1.00) 0.036* 0.99 (0.97–1.02) 0.453
IgA 1.00 (1.00–1.00) 0.075
C3 0.98 (0.95–1.00) 0.094
C4 1.02 (0.97–1.07) 0.447
Blood urea nitrogen 1.02 (1.01–1.03) 0.005**
Creatinine 1.06 (0.96–1.17) 0.277
eGFR 0.97 (0.94–0.99) 0.011* 1.00 (0.96–1.03) 0.915
ANA
 Negative Reference Reference
 Positive 1.56 (0.19–12.84) 0.678
ANCA
 Negative Reference Reference
 Positive 7.59 (0.88–65.49) 0.065

Cox proportional hazard regression.

*p<0.05,

**p<0.01.