Table 3.
Serum Chemistries from G2e3 and Prkd1 KO Mice
| Analytes | Units | G2e3 | Prkd1 | ||
|---|---|---|---|---|---|
| WT | KO | WT | KO | ||
| Sodium | mmol/L | 151 ± 2 | 149 ± 1 | 148 ± 1 | 147 ± 1 |
| Potassium | mmol/L | 4.6 ± 0.5 | 4.5 ± 0.6 | 4.5 ± 0.2 | 4.9 ± 0.3 |
| Chloride | mmol/L | 115 ± 2 | 114 ± 2 | 112 ± 2 | 113 ± 2 |
| BUN | mg/dL | 26 ± 11 | 25 ± 4 | 26 ± 5 | 28 ± 7 |
| Creatinine | mmol/dL | 0.5 ± 0.1 | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.4 ± 0.1 |
| Glucose | mg/dL | 125 ± 25 | 174 ± 26* | 232 ± 15 | 223 ± 57 |
| Calcium | mg/dL | 9.1 ± 0.6 | 8.9 ± 0.3 | 10.2 ± 0.1 | 9.9 ± 0.4 |
| Phosphate | mg/dL | 8.0 ± 3.2 | 8.4 ± 1.1 | 8.4 ± 1.3 | 6.9 ± 1.1 |
| Albumin | g/dL | 2.9 ± 0.5 | 3.2 ± 1.7 | 3.4 ± 0.3 | 3.4 ± 0.2 |
| Cholesterol | mg/dL | 126 ± 32 | 131 ± 50 | 115 ± 28 | 111 ± 33 |
| Triglycerides | mg/dL | 108 ± 53 | 122 ± 41 | 110 ± 51 | 97 ± 59 |
| Total bilirubin | mg/dL | 0.5 ± 0.3 | 0.6 ± 0.7 | 0.3 ± 0.2 | 0.5 ± 0.3 |
| Alkaline phosphatase | IU/L | 88 ± 27 | 87 ± 25 | 93 ± 26 | 99 ± 35 |
| Alanine aminotransferase | IU/L | 57 ± 36 | 95 ± 52 | 32 ± 7 | 62 ± 41 |
Notes: For each KO line, blood was drawn on 8 fed KO mice (4 male, 4 female) and 4 fed WT mice (2 male, 2 female) at 15 weeks of age as described in Materials and Methods. The only comparison where KO and WT data differ is in bold font; *P < 0.05.
Abbreviations: WT, wild-type; KO, knockout; mmol, millimole; L, liter; mg, milligram; dL, deciliter; g, gram; IU, international units.