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. 2020 Jul 27;13:7213–7227. doi: 10.2147/OTT.S246471

Figure 1.

Figure 1

The association between the expression of the miR-3609/EPAS-1 axis with the prognosis of advanced HCC patients after receiving sorafenib treatment. The expression of EPAS-1 and miR-3609 in clinical specimens was examined, and the patients were divided into two groups according to the median expression level (high or low). The OS (overall survival) and TTP (time to progress) of patients were analyzed. (A and B) The prognosis of patients with high endogenous EPAS-1 expression (EPAS-1-high) or low endogenous EPAS-1 expression (EPAS-1-low). (C) The potential binding sites of miR-3609 in the 3′UTR of the epas-1 mRNA. (D and E) Prognosis of patients with high endogenous miR-3609 expression (miR-3609-high) or low endogenous miR-3609 expression (miR-3609-low); *P < 0.05.