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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Endocr Relat Cancer. 2020 Apr;27(4):261–274. doi: 10.1530/ERC-19-0431

Figure 2. MDSCs levels are elevated in uterine-specific Tsc2-null mice.

Figure 2.

A. Representative dot plots of granulocytic, or PMN-MDSC levels in blood and organs of 18-week old KO vs. WT mice. Dot plots depict Ly6G versus Ly6C expression gated on CD11b live cells in uterus, lung, and peripheral blood. B. PMN-MDSCs (Ly6C+/Ly6G+) in uterus, lung and peripheral blood were quantified in KO mice relative to WT mice and analyzed using unpaired two-tailed t test (n=4/group, *p<0.05, **p<0.01). C. Representative immunofluorescence staining for Ly6G (infiltrating PMN-MDSCs) and adjacent H&E stains in KO vs. WT mice is shown (top; scale bar, 100μm) and corresponding H&E staining on serial sections (bottom; scale bar, 100μm).