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. Author manuscript; available in PMC: 2021 Jan 22.
Published in final edited form as: Nature. 2020 Jul 22;583(7818):845–851. doi: 10.1038/s41586-020-2513-4

Extended Data Figure 3. Phenotypic differences between B-ALL cells driven by oncogenic STAT5 or ERK reflect developmental rewiring during early B-cell development.

Extended Data Figure 3.

a-g, Eight different B-ALL PDX samples (Supplementary Table 5) were analyzed by flow cytometry for CRLF2 (a), VpreB (b), CD21 (c), IgM (d), Ig-κλ (e), CD34 (f) and IgM (g) surface expression. Normal CD19+ B-cell precursors from a normal bone marrow sample and mature B-cells from a normal peripheral blood sample, as well a mature B-cell lymphoma cell lines were used as reference. Representative FACS plots from 3 independent experiments.