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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Pediatr Emerg Care. 2021 Dec 1;37(12):e1345–e1350. doi: 10.1097/PEC.0000000000002035

Table 2.

Test characteristics across a range of cut-points of plasma β-hydroxybutyrate (BOHB) in the prediction of diabetic ketoacidosis among pediatric emergency department patients.

BOHB Cut-point (mmol/L) Sensitivity (%) Specificity (%) Positive Predictive Value (%) Negative Predictive Value (%) Correctly Classified (%) LR+ LR−

≥ 1 98.3 47.6 44.1 98.5 62.6 1.88 0.04
≥ 2 96.6 65.3 54.3 97.9 74.6 2.78 0.05
≥ 3 94.3 79.9 66.4 97.1 84.2 4.69 0.07
≥ 4 86.9 89.0 77.3 94.2 88.4 7.90 0.15
≥ 5 77.3 94.5 85.5 90.8 89.4 14.04 0.24
≥ 6 64.8 97.9 92.6 86.7 88.1 30.08 0.36
≥ 7 48.3 99.0 95.5 81.8 84.0 50.47 0.52
≥ 8 30.7 100.0 100.0 77.4 79.5 --- 0.69

Likelihood ratio positive (LR+); Likelihood ratio negative (LR-)s