Table 1.
Age and cognitive ability assessment in Group MS and Group NT patients with means and standard deviations.
| Chrono-logical age at baseline | Chrono-logical age at last visit | Number of visits | Develop-mental age at baseline | Develop-mental age at last visit | Change in develop-mental age | Elapsed time from baseline to last visit | Develop-mental quotient baseline | Develop-mental quotient last visit | |
|---|---|---|---|---|---|---|---|---|---|
| Group Group MS | |||||||||
| 1.G140V | 28 | 47 | 6 | 24 | 26 | 2 | 19 | 86 | 55 |
| 2.K234N | 15⁎ | 78 | 12 | 11 | 39 | 28 | 63 | 73 | 50 |
| 3. R468Q | 45 | 116 | 9 | 30 | 27 | −3 | 71 | 67 | 23 |
| 4. K236N | 46 | 60 | 3 | 36 | 38 | 2 | 14 | 78 | 63 |
| 5. R88H | 37 | 69 | 3 | 18 | 19 | 1 | 32 | 49 | 28 |
| 6. Q121R | 30 | 95 | 8 | 18 | 16 | −2 | 65 | 60 | 17 |
| Mean | 37.2 | 77.5 | 6.8 | 22.8 | 27.5 | 4.7 | 44.0 | 68.8 | 39.4 |
| Standard deviation | 8.3 | 24.9 | 3.5 | 9.1 | 9.5 | 11.6 | 25.3 | 13.3 | 19.2 |
| Group NT | |||||||||
| 1. W337X | 43 | 90 | 7 | 22 | 20 | −2 | 47 | 51 | 22 |
| 2.Y242X | 36 | 64 | 3 | 15 | 19 | 4 | 28 | 42 | 30 |
| 3. 163delG | 22 | 83 | 7 | 18 | 12 | −6 | 61 | 82 | 14 |
| 4. Whole gene deletion | 34 | 78 | 10 | 24 | 12 | −12 | 44 | 71 | 15 |
| 5. Recom-bination with IDS 2 | 35 | 56 | 2 | 23 | 26 | 3 | 21 | 66 | 46 |
| 6. Recom-bination with IDS 2 | 39 | 54 | 2 | 19 | 21 | 2 | 15 | 49 | 39 |
| 7. Recom-bination with IDS 2 | 6⁎ | 58 | 8 | 5 | 34 | 29 | 52 | 83 | 59 |
| Mean | 34.8 | 69.0 | 5.6 | 18.0 | 20.6 | 2.6 | 38.3 | 63.4 | 32.2 |
| Standard deviation | 7.1 | 14.5 | 3.2 | 6.5 | 7.7 | 13.0 | 17.1 | 16.4 | 16.7 |
All timed data is in months with the exception of gain/loss which is calculated by year.
⁎
child is under 1.5 years of age