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Decoy-CTCFs Repress Tumorigenesis In Vitro and In Vivo
(A) Soft agar assay showed fewer and smaller colonies in dsCTCF or deCTCF expressed ocular melanoma cells. (B and C) Subcutaneous xenograft model demonstrated that the tumor volume (B) and weight (C) of dsCTCF expressed groups was significantly reduced. (D) Hematoxylin and eosin stain of tumor tissues showed more necrosis regions in dsCTCF expressed group.
