Table 2.
Mean/Standard Deviation of BMA Parameter Estimates
| Matrices (Condition) | Model Parameters | Mean (in HZ) |
Standard Deviation |
Effect Size |
t-Tests (df = 44) |
|||
|---|---|---|---|---|---|---|---|---|
| Controls | PTSD | Controls | PTSD | Cohen’s d | t-statistic | p-value | ||
| C(NW) | PAG | −0.1371 | −0.2863 | 0.0469 | 0.0472 | 3.1732 | 113.612 | < 0.001 |
| C(TW) | PAG | −0.2433 | −0.3223 | 0.0490 | 0.0493 | 1.6134 | 30.729 | < 0.001 |
| A | PAG → PAG | −0.0362 | −0.0377 | 0.0275 | 0.0240 | 0.0582 | 0.0389 | 0.844 |
| PCN → PCN | −0.0155 | −0.0119 | 0.0281 | 0.0242 | −0.1376 | 0.2175 | 0.643 | |
| mPFC → mPFC | −0.0223 | −0.0104 | 0.0278 | 0.0248 | −0.4524 | 2.3432 | 0.133 | |
| PAG → PCN | 0.0016 | 0.0362 | 0.0222 | 0.0211 | −1.5981 | 29.055 | < 0.001 | |
| PAG → mPFC | 0.0116 | 0.0352 | 0.0251 | 0.0225 | −0.9916 | 44.237 | < 0.001 | |
| PCN → PAG | 0.0261 | 0.0422 | 0.0261 | 0.0228 | −0.6585 | 5.0324 | 0.031 | |
| mPFC → PAG | −0.0004 | 0.0251 | 0.0256 | 0.0227 | −1.0547 | 13.131 | 0.002 | |
| B(NW) | PAG → PCN | 0.2135 | 0.4256 | 0.1768 | 0.1641 | −1.2447 | 17.670 | < 0.001 |
| PAG → mPFC | 0.1435 | 0.2297 | 0.1944 | 0.1788 | −0.4619 | 2.4358 | 0.126 | |
| PCN → PAG | 0.1204 | 0.1789 | 0.2124 | 0.1863 | −0.2934 | 0.9869 | 0.326 | |
| mPFC → PAG | 0.1021 | 0.1335 | 0.2096 | 0.1831 | −0.1599 | 0.2951 | 0.589 | |
| B(TW) | PAG → PCN | 0.3287 | 0.5069 | 0.1774 | 0.1591 | −1.0591 | 12.833 | <0.001 |
| PAG → mPFC | −0.0236 | 0.1841 | 0.1941 | 0.1756 | −1.1236 | 14.419 | <0.001 | |
| PCN → PAG | −0.0361 | 0.1381 | 0.2101 | 0.1862 | −0.8791 | 8.8502 | 0.005 | |
| mPFC → PAG | −0.0402 | 0.0623 | 0.2112 | 0.1824 | −0.5208 | 3.1119 | 0.085 | |
Table 2: Means and standard deviation values for BMA model parameters are represented for each group. For endogenous connections, whereas positive parameter values indicate that an increase in activity in the one region results in an increase in the rate of change in the activity of the connected region, negative parameter values indicate that an increase in activity of the one region results in a decrease in the rate of change in activity of the connected region. Bold font represents significance at p ≤ 0.0029.
Abbreviations: PTSD: posttraumatic stress disorder; C(NW): neutral stimulus condition direct connections; C(TW): trauma-related stimulus condition direct connections; A: endogenous connections; B(NW): neutral stimulus condition modulatory connections; B(TW): trauma-related stimulus condition modulatory connections; PAG: periaqueductal gray; PCN: precuneus; mPFC: medial prefrontal cortex.