Table 2.
Clinicopathological characteristics of the selected patients
| Total N = 8056 |
N = 967 | N0 N = 7089 |
P | |
|---|---|---|---|---|
| Tumor size (cm) | 0.015 | |||
| < 1 | 1442 (17.9) | 169 (17.48) | 1273 (17.96) | |
| 1–1.9 | 1736 (21.55) | 231 (23.89) | 1505 (21.23) | |
| 2–2.9 | 1160 (14.4) | 137 (14.17) | 1023 (14.43) | |
| 3+ | 1482 (18.4) | 200 (20.68) | 1282 (18.08) | |
| Not stated | 2236 (27.76) | 230 (23.78) | 2006 (28.3) | |
| Histology | < 0.001 | |||
| Adenocarcinoma | 7835 (97.26) | 920 (95.14) | 6915 (97.55) | |
| Mucinous carcinoma | 221 (2.74) | 47 (4.86) | 174 (2.45) | |
| CEA* | < 0.001 | |||
| Positive | 457 (5.67) | 75 (7.76) | 382 (5.39) | |
| Negative | 3123 (38.77) | 439 (45.4) | 2684 (37.86) | |
| Borderline/unknown | 4476 (55.56) | 453 (46.85) | 4023 (56.75) | |
| Grade | < 0.001 | |||
| Well-differentiated | 1605 (19.92) | 116 (12.0) | 1489 (21) | |
| Moderately differentiated | 5054 (62.74) | 625 (64.63) | 4429 (62.48) | |
| Poorly differentiated | 563 (6.99) | 162 (16.75) | 401 (5.66) | |
| Undifferentiated | 55 (0.68) | 10 (1.03) | 45 (0.63) | |
| Unknown | 779 (9.67) | 54 (5.58) | 725 (10.23) | |
| Year | 0.112 | |||
| 2004–2006 | 1680 (20.85) | 216 (22.34) | 1464 (20.65) | |
| 2007–2009 | 2998 (37.21) | 331 (34.23) | 2667 (37.62) | |
| 2010–2012 | 3378 (41.93) | 420 (43.43) | 2958 (41.73) | |
| Age (years) | < 0.001 | |||
| Up to 49 | 731 (9.07) | 114 (11.79) | 617 (8.7) | |
| 50–64 | 3101 (38.49) | 455 (47.05) | 2646 (37.33) | |
| 65–79 | 3162 (39.25) | 324 (33.51) | 2838 (40.03) | |
| 80+ | 1062 (13.18) | 74 (7.65) | 988 (13.94) | |
| Gender | 0.257 | |||
| Male | 3924 (48.71) | 454 (46.95) | 3470 (48.95) | |
| Female | 4132 (51.29) | 513 (53.05) | 3619 (51.05) | |
| Race | 0.321 | |||
| Black | 988 (12.26) | 117 (12.1) | 871 (12.29) | |
| White | 6371 (79.08) | 753 (77.87) | 5618 (79.25) | |
| Others | 647 (8.03) | 88 (9.1) | 559 (7.89) | |
| Unknown | 50 (0.62) | 9 (0.93) | 41 (0.58) | |
| Marital status | 0.007 | |||
| Married | 4865 (60.39) | 626 (64.74) | 4239 (59.8) | |
| Single/widowed | 2042 (25.35) | 228 (23.58) | 1814 (25.59) | |
| Other/unknown | 1149 (14.26) | 113 (11.69) | 1036 (14.61) | |
| Primary site | < 0.001 | |||
| Cecum | 1781 (22.11) | 204 (21.1) | 1577 (22.25) | |
| Ascending colon | 1989 (24.69) | 181 (18.72) | 1808 (25.5) | |
| Hepatic flexure | 399 (4.95) | 42 (4.34) | 357 (5.04) | |
| Transverse colon | 615 (7.63) | 61 (6.31) | 554 (7.81) | |
| Splenic flexure | 157 (1.95) | 13 (1.34) | 144 (2.03) | |
| Descending colon | 410 (5.09) | 49 (5.07) | 361 (5.09) | |
| Sigmoid colon | 2705 (33.58) | 417 (43.12) | 2288 (32.28) | |
|
Total lymph nodes Median (IQR*) |
17 (14–22) | 17 (14–22) | 17 (14–22) | 0.375 |
| Radiation | < 0.001 | |||
| None | 8043 (99.84) | 959 (99.17) | 7084 (99.93) | |
| Postoperative | 13 (0.16) | 8 (0.83) | 5 (0.07) | |
| Cause of death | < 0.001 | |||
| Alive | 6650 (82.55) | 786 (81.28) | 5864 (82.72) | |
| Dead from cancer | 322 (4.00) | 91 (9.41) | 231 (3.26) | |
| Dead not from cancer | 1084 (13.46) | 90 (9.31) | 994 (14.02) | |
| Follow-up time (months) | 68 (47–94) | 66 (45–94) | 66 (45–94) | 0.176 |
*CEA carcinoembryonic antigen, IQR interquartile range