Fig. 1.

General mechanism of action of antimicrobial peptides; a represents attraction step where electrostatic bonding arises between negatively charged peptidoglycan layer of the bacterial cell membrane and amphiphilic polypeptide structure; b represents attachment step where the AMPs binds to Lipopolysaccharide (LPS) layer of Gram-negative cell wall and a teichoic acid layer of Gram-positive cell wall; c Represents the final peptide insertion step where following attachment the peptide forms a pore and thus disrupts the bacterial cell membrane