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. 2020 Jun 19;4(8):1168–1182. doi: 10.1002/hep4.1537

Fig. 4.

Fig. 4

Tryptophan metabolism. (A) Relative abundance of microbial superpathway of L‐tryptophan biosynthesis. G5 versus G2: P = 0.039. Fecal and serum level of tryptophan (B), indole‐3‐propionic acid (C), and indole‐3‐lactic acid (D). (E) Area under the curve using different predictors related to tryptophan metabolism. Alive group, n = 38; deceased group, n = 5. P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Abbreviations: AH_F0_2, patients with alcoholic hepatitis without cirrhosis; AH_F3_4, patients with alcoholic hepatitis with cirrhosis; AH_c, patients with alcoholic hepatitis with cirrhosis; AUD_nc, patients with alcohol use disorder without cirrhosis; AUD_c, patients with alcohol use disorder with cirrhosis; Ctrl, control; AUC, area under the curve; G1, controls; G2, patients with alcohol use disorder without cirrhosis; G3, patients with alcohol use disorder with cirrhosis; G4, patients with alcoholic hepatitis without cirrhosis; G5, patients with alcoholic hepatitis with cirrhosis; N.S., not significant.