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. 2020 Jul 31;11:3862. doi: 10.1038/s41467-020-17618-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Allosteric correlations measured by CHESCA. Blank rows and columns are caused by missing data for residues 1, 2, 13, 14, 15, 16, 18, 19, 59, 60, 61, 65, 82, 90, 92, and 110. CHESCA data are in Supplementary Data 1. b Allosteric correlations measured by CHESCA subjected to Gaussian filtration. Dashed boxes, including the colored boxes (I, II, III, IV, and V) and the white boxes, are common regions to CHESCA and Ohm analysis. c Allosteric correlations predicted by Ohm. Regions in dashed circles only appear in allosteric correlations predicted by Ohm. d The true-positive ratio of allosteric correlations predicted by Ohm, native contacts, the shortest paths lengths, PRS, and the hitting time. Data of all methods for the comparison can be found in Supplementary Data 3. e Tertiary structure of CheY Regions indicated in panels b and e are labeled. The green cylinders represent the allosteric pathway.