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. 2020 Jul 31;10:12980. doi: 10.1038/s41598-020-69547-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Experimental results of impact of glucose concentration variation in samples with DI water + serum + saline solution. (a) Frequency shift of the sensor as the response to alternatively changing the glucose concentration from zero to 200 mM/l. It could be seen that, the proposed sensor presents a stable and repeatable response over time. (b) Frequency shift of the sensor as the response of small variation of glucose concentration. It could be seen that, according to introducing of the skin between the sensor and the sample, the overall sensitivity is reduced to 38 kHz/1 mM/l of glucose concentration variation.